Hans P. Nazarloo, M.D. Ph.D.

Senior research scientist

Dr. Nazarloo is trained in molecular neuroendocrinology, neuroimmunology and clinical cardiology. He has worked with Dr. Sue Carter at the University of Illinois at Chicago, Research Triangle Institute and University of North Carolina (originally as a Research Assistant Professor, then Research Associate Professor, and Senior Neuroscientist), where he developed his research with prairie voles. His research interest is to understand mechanisms through which stressors across the life-span regulate physiology and behavior.

Dr. Nazarloo has a long-standing interest in validation of the ELISA Assays and a better understanding of sex differences, especially as they related to female health and behavior. Currently, he is conducting exciting work on validating oxytocin in saliva as well as working on epigenetic mechanisms involved in the oxytocin receptor gene.

 hnazarlo@iu.edu
 (812) 855-7686

428 Lindley Hall
Indiana University
Bloomington, IN 47405

Education

  • Ph.D., Kochi Medical School, 2003
  • M.D., Carol Davila University of Medicine, 1996

Research interests

  • Sex differences
  • Epigenetic mechanisms of oxytocin receptor gene
  • ELISA Assays validation

Selected publications

  • Rubin LH, Connelly JJ, Reilly JL, Carter CS, Drogos LL, Pournajafi-Nazarloo H, Ruocco AC, Keedy SK, Matthew I, Tandon N, Pearlson GD, Clementz BA, Tammiga CA, Gershon ES, Keshavan MS, Bishop JR, Sweeney JA: “Sex and diagnosis specific associations between DNA methylation of the oxytocin receptor gene, emotion processing, and temporal and limbic-prefrontal structures in psychotic disorders”. Biological Psychiatry 2016; 1:141-151.
  • Lancaster K, Carter CS, Pournajafi-Nazarloo H, Karaoli T, Lillard TS, Jack A, Davis JM, Morris JP, Connelly JJ: “Plasma oxytocin explains individual differences in neural substrates of social perception”. Front Hum Neurosci 2015; 9:132.
  • Rubin LH, Carter CS, Bishop JR, Pournajafi-Nazarloo H, Drogos LL, Hill SK, Ruocco AC, Keedy SK, Reilly JL, Keshavan MS, Pearlson GD, Tamminga CA, Gershon ES, Sweeney JA: “Reduced Levels of Vasopressin and Reduced Behavioral Modulation of Oxytocin in Psychotic Disorders.”. Schizophr Bull. 2014;40 (6):1374-84.
  • Pournajafi-Nazarloo H, Kenkel B, Sanzenbacher L, Yee J, Hashimoto K, Carter CS: "Exposure to chronic isolation modulates receptors mRNAs for oxytocin and vasopressin in the hypothalamus and heart". Peptides 2013;43:20-26.
  • Gouin JP, Carter CS, Pournajafi-Nazarloo H, Malarkey WB, Loving TJ, Stowell J, KiecoltGlaser JK:: “Plasma vasopressin and interpersonal functioning”. Biological Psychology. 2012;91(2):270-4.
  • Dai L, Carter CS, Ying J, Bellugi U, Pournajafi-Nazarloo H, Korenberg JR: “Oxytocin and Vasopressin are Dysregulated in Williams Syndrome, A Genetic Disorder Affecting Social Behavior”. PLoS ONE 2012; 7(6): e38513.
  • Grippo AJ, Pournajafi-Nazarloo H, Sanzenbacher L, Trahanas DM, McNeal N, Clarke DA, Porges SW, Carter CS: “Peripheral oxytocin administration buffers autonomic but not behavioral responses to environmental stressors in isolated prairie voles”. Stress 2012; 15(2):149-61.
  • Pournajafi-Nazarloo H, Partoo L, Yee J, Stevenson J, Sanzenbacher L, Kenkel W, Mohsenpour SR, Hashimoto K and Carter CS: “Effects of social isolation on mRNA expression for corticotrophin-releasing factor receptors in prairie voles”. Psychoneuroendocrinology 2011; 36: 780-789.
  • Pournajafi-Nazarloo H, Partoo L, Sanzenbacher L, Esmaelzadeh M, Paredes J, Hashimoto K, Azizi F, Carter CS: “Social isolation modulates corticotropin-releasing factor type 2 receptor, urocortin 1 and urocortin 2 mRNAs expression in the cardiovascular system of prairie voles”. Peptides 2009; 30:940-946.
  • Pournajafi-Nazarloo H, Partoo L, Sanzenbacher L, Parades J, Hashimoto K, Azizi F, Carter CS: “Stress differentially modulates mRNA expression for corticotrophin-releasing factor receptors in hypothalamus, hippocampus and pituitary of prairie voles”. Neuropeptides 2009; 43(2):113-23.
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